http://www.youtube.com/watch?v=WMn-cJHzF8A

Robert Scoble suggests that a new curator should focus on a niche, something very specific that no one else is doing like curating content about the pets that live at the White House. However, if you want more of the Cabinet of Curiosities feel, you can curate content from a broader theme. An example of a niche Hot Topic would be The Loch Ness Monster, a broader theme would be something like Unexplained Phenomenon (which would include Nessie as well as Bigfoot, Crop Circles, and Alien Abductions). 

For further information, you can check out Robin Good's Organizing and Curating Content on a Subject May Actually Be The Best Way To Learn It

What Topic or Theme would you like to curate? share in a comment below.